この項目では、鎮咳去痰薬について説明しています。ロックバンドについては「コデイン (バンド)」をご覧ください。
Other individuals Have got a genetic variance which makes them course of action codeine a lot quicker; this can cause bigger doses of codeine accumulating speedier, and an increased prospect of side effects.
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Glaucoma. Glaucoma is usually a condition which could cause difficulty seeing or blindness due to harm to the optic nerve as part of your eye. Promethazine/phenylephrine/codeine may well maximize strain Within the eye and worsen slender-angle glaucoma.
Ten in the 64 conditions mentioned the standing of cytochrome P450 isoenzyme 2D6 (CYP2D6) genotype. Seven of these sufferers were ultra-swift metabolizers, five of whom died. Ultra-speedy metabolizers of substrates of CYP2D6 transform codeine in their bodies also promptly into probably dangerously higher levels of morphine, the active kind of codeine, contributing to everyday living-threatening or lethal respiratory melancholy. The a few other individuals have been comprehensive metabolizers, with a person Dying.
オーストラリアとカナダでは、コデインは規制されているが、許可された薬剤師による最大15mg/錠での調合による入手が処方箋なしで可能である。
Peripheral Vascular Condition. Promethazine/phenylephrine/codeine really should not be applied When you have peripheral vascular disease, which is a situation that affects blood vessels. Promethazine/phenylephrine/codeine could make this problem even worse.
Epinephrine – As a result of prospective for promethazine to reverse epinephrine’s vasopressor result, epinephrine shouldn't be applied to deal with hypotension associated with promethazine overdose.
Indications normally seem in the course of the very first few days of daily life. Promethazine administered to the pregnant woman within two months of shipping may perhaps inhibit platelet aggregation inside the new child.
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The subsequent era is holding the custom alive, to provide both equally the area people and sufferers across North The united states and Over and above.
Carry on to consider codeine for as long as your physician tells you to. For those who end using codeine abruptly, you could possibly expertise withdrawal signs and symptoms.
Small Hypertension (Hypotension). Promethazine/phenylephrine/codeine might lead to very low blood pressure level. If you really feel faint or dizzy, lie down. Inform your Health care supplier straight away When you've got any of the next signs or symptoms of low hypertension.
Due to this fact, we're requiring a number of modifications towards the labels read more of all prescription medicines containing these prescription drugs. These new actions further more limit using these medicines over and above our 2013 restriction of codeine use in youngsters younger than eighteen a long time to take care of discomfort right after operation to remove the tonsils and/or adenoids. We at the moment are introducing: